Endocrine Abstracts

Introduction: Adiposity has been well known to influence blood pressure. Adipokines are peptides secreted from the adipose tissue. TNF-alpha and IL-6 are pro-inflammatory adipokines while adiponectin and leptin have been known to be influencing vascular function. The influence of adipokines on blood pressure is not yet known. Our hypothesis was that all adipokines positively influenced both systolic and diastolic blood pressure.Patients and methods: One ...

Introduction: Propensity to centripetal adiposity is an ethnic characteristic amongst South Asians, which may underlie the excess risk for both coronary heart disease (CHD) and diabetes in this population. Circulating levels of adipocytokines (hormones which include leptin, adiponectin, tumour necrosis factor (TNF-alpha)) and C-reactive protein (CRP) reflect the adipose tissues endocrine and metabolic activity, and are implicated in CHD.Methods: We compa...

Introduction: Compared to ethnically European men, Pakistani origin men living in the UK have a lower circulating total and free testosterone level, corresponding with greater central adiposity and higher insulin resistance. Within a South Asian group we have now examined the effect of migration to the UK on male testosterone level.Methods: Circulating testosterone concentration was measured by automated immunoassay in 97 Gujarati males resident in India...